Hydroxypropyl Methylcellulose (HPMC), 40lbs

Attention: HPMC and Sepimax Zen can both thicken 70% isopropyl alcohol at 3%.

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Pricing is in lieu of Customer Rewards Points or any other discount. At times, this may be a special order and will have a lead time of 6-8 weeks. Call us to verify stock on hand if you need it sooner. Lead time is subject to change.

CAS No. -65-3

Hydroxypropyl Methylcellulose (HPMC) serves multiple functions, including lubricant, foam enhancer, stabilizer, thickener, emulsion stabilizer, and film former for hair and skin care products. HPMC is particularly beneficial in surfactant systems due to its foam-enhancing properties, which facilitate the formation of bubble structures, resulting in richer and longer-lasting lather. Moreover, HPMC exhibits high tolerance for salt and alcohol.

Techniques for Dispersion

• The preferred method is to begin by heating approximately one-third of the total formulation water to 167°F (75°C) or higher. Add the HPMC to the vortex of agitated and heated water and mix until fully dispersed. HPMC will not dissolve at this temperature. Upon complete dispersion, add the remaining water at room temperature or colder and continue mixing for 30 minutes after the total solution has cooled to 77°F (25°C) or less. Then, proceed with the formulation.
• If heating is not an option, it is advisable to create a slurry of HPMC in a non-solvating medium such as glycerin or PEG, then add the slurry to the vortex of vigorously agitated water. Directly adding HPMC to cold water is not recommended; however, if necessary, it must be done very slowly under vigorous agitation. Be prepared for longer mixing times to achieve complete dissolution.

INCI: Hydroxypropyl Methylcellulose

California Prop 65 Statement: This statement is made in compliance with the California Safe Drinking Water and Toxic Enforcement Act. This product is not known to the State of California to cause cancer, birth defects, or other reproductive harm.

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1. Hydroxypropyl Methylcellulose exhibits thermal gelation properties, being soluble in cold water while remaining insoluble in hot water. When stirred in cold water, it can dissolve completely, yielding a transparent solution. Some grades remain insoluble in hot water over 60°C and can only swell. This characteristic can be utilized for washing and purification processes to reduce costs, lower pollution, and enhance production safety.

2. As a non-ionic mixed cellulose ether, Hydroxypropyl Methylcellulose has no ionic charge in its solution and does not react with metal salts or ionic compounds. This property is highly beneficial in the pharmaceutical field, allowing it to maintain efficacy without interference.

3. Hydroxypropyl Methylcellulose demonstrates strong enzyme resistance, which increases with a higher degree of substitution. This advantage makes it preferable for the storage of pharmaceutical products over other sugars and starches, reducing the likelihood of mold growth. It finds wide applications in the paint and food industries.

4. Hydroxypropyl Methylcellulose is metabolically inert, meaning it will not be absorbed or metabolized when used as a pharmaceutical excipient. In food applications, it does not contribute caloric value and is suitable for low-calorie products, offering no salt and no alterations in immunogenicity, making it ideal for people with diabetes.

5. HPMC solutions possess excellent film-forming abilities, making them advantageous for tablets, pills, and coatings. The resulting film is colorless, transparent, and robust. When glycerin is added, the film's flexibility can be enhanced.

Product:

SidleyCel Hydroxypropyl Methylcellulose

For more details, kindly visit HPMC Water Retention.