3 types of granulation

Granulation plays a vital role in numerous manufacturing sectors, particularly within pharmaceuticals, agriculture, and food production. Recognizing the various types of granulation is essential, as it can greatly affect the quality and efficiency of the final product. This article will delve into the 3 types of granulation and their respective applications, offering valuable insights and information that underline their significance.

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1. Dry Granulation

Dry granulation is a method that compacts granular materials without the inclusion of liquids. This approach is particularly favored when dealing with materials prone to degradation due to moisture or heat.

As per a report from Grand View Research, the dry granulation market is anticipated to achieve USD 5.4 billion by 2027, with a CAGR of 6.5% starting from 2020. This upward trend is attributed to the technique's benefits, such as improved flow properties and simplified powder handling.

Applications of Dry Granulation

This granulation method finds frequent use within the pharmaceutical sector, particularly in tablet production. Research indicates that around 75% of all tablet formulations leverage dry granulation, praised for its cost-effectiveness and efficiency.

2. Wet Granulation

Wet granulation involves incorporating a liquid binding agent to create granules. This method enhances the flow characteristics and compressibility of powders, making it particularly suitable for a range of pharmaceutical applications.

A study published in the Journal of Pharmaceutical Sciences highlighted that wet granulation is employed in over 90% of tablet manufacturing processes. This method is particularly advantageous as it provides better blend homogeneity and enhances content uniformity.

Benefits of Wet Granulation

The advantages of wet granulation can be particularly noted in the development of controlled-release formulations. Research in pharmaceutical analytics has revealed that approximately 80% of controlled-release drug products utilize wet granulation to maximize drug release efficiency.

3. Extrusion Granulation

Extrusion granulation is an innovative technique where a mixture is forced through a die, resulting in uniformly sized granules. This method is increasingly popular due to its capability to generate high-quality granules with precise size distribution.

The global granulation equipment market, which encompasses extrusion granulators, is forecasted to grow from USD 2.2 billion in 2020 to USD 3.5 billion by 2025, according to Mordor Intelligence. Notably, extrusion granulation holds nearly 30% of the overall granulation market due to its scalability and efficiency.

Applications in Various Industries

Extrusion granulation is widely utilized in the manufacturing of pharmaceuticals and food products. For instance, nearly 70% of dietary supplement manufacturers have transitioned to extrusion techniques for granulation, reporting enhanced product quality and shorter production durations.

Conclusion

To sum up, the 3 types of granulation—dry granulation, wet granulation, and extrusion granulation—offer unique advantages and applications across a range of industries. As the market landscape evolves, having a grasp of these methods is crucial for manufacturers aiming to enhance both efficiency and product quality. The statistics and insights shared in this article aim to assist in informed decision-making while underscoring the critical nature of granulation processes in modern manufacturing.

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